"Doc, I took that saliva test you wrote about in a previous blog, The Best Hormone Test and the test said I had a P/E Ratio of 32. I know that isn't good! What should be my first step?"
My wife discovered her P/E Ratio when she stopped ovulating at the age of 42, and she had an even lower score. When your P/E Ratio is 100 or lower, you are diagnosed as being estrogen-dominant. If you recall from the last blog post, the symptoms usually associated with specific P/E Ratios are:
!00 to 1 - Rapid weight gain and the inability to lose weight
75 to 1 - Sleeping disorders and more weight gain
50 to 1 - Hormonal induced anxiety and depression
25 to 1 - Loss of interest in being intimate and social
Once my wife was diagnosed with Estrogen Dominance, the first step I had my wife take was to supplement with 200 mg of DIM nightly.
Before you run off and start taking DIM, discussing its supplementation with your healthcare practitioner is a must.
DIM
DIM (diindolylmethane) is a natural compound derived from cruciferous vegetables that many women and men use in their "Third Act" of life to calm the hormone mess that occurs.
Below are four reasons I suggested to my wife and patients to supplement with DIM.
DIM and Estrogen Metabolism
Recall that the liver breaks down food into protein, fats, and carbohydrates. It does the same with estrogens. The liver doesn't break down estrogens into macronutrients; it breaks them down into three metabolites. Two metabolites are harmful: carcinogenic and fat-storing, and one is less carcinogenic and fat-storing. The "bad" estrogen metabolites are associated with breast, ovarian, and prostate cancer.
DIM doesn't change your hormone levels; it makes estrogen safer.
Imagine taking a Sunday drive along an ocean-view two-lane highway. One of the lanes has been closed due to a collapse. You pull up to the collapsed area of the road, and a traffic officer stops the traffic flow. Your car is estrogen, and the traffic officer is DIM. DIM sends estrogen down the safest route.
DIM and The Detoxification Process
We optimize your health in the third strand of the HOPE Protocol, the Purification Strand. We begin by optimizing your liver, as fatty livers hinder hormone and weight optimization.
DIM works as a liver detoxifier. The liver has three primary detox functions:
It filters toxins from our bodies,
burns them,
and flushes the toxin's ashes from your body.
DIM improves all three functions.
Regarding estrogens, DIM assists the liver in eliminating excess or “misbehaving” estrogen, which can help reduce the risk of estrogen dominance. And estrogen-related cancers
Provides Anti-inflammatory Benefits:
The primary source cause of our deaths is inflammation. Inflammation is the silent killer that is behind the cause of most cancers, diabetes, heart disease, strokes, and Alzheimer's.
Technically, DIM reduces inflammation by inhibiting the expression of pro-inflammatory cytokines and by down-regulating transcription factors like NF-κB and AP-1,
DIM blocks the pathways that inflammation signals travel, potentially impacting conditions like arthritis and other inflammatory diseases that flare up because of menopausal-related inflammation.
Provides Antioxidant Benefits:
When combustion occurs in our cells to make energy, oxidants are produced—think of them as the toxic exhaust gas engines produce.
Oxidants are molecules missing an electron. They bounce around in your cell like a pinball, trying to steal an electron, and when they succeed, they cause internal cellular damage.
Antioxidants neutralize these oxidants by donating an electron. DIM is an excellent electron donor.
SUMMARY
In a nutshell, DIM was the first choice tool I suggested for my wife to use as soon as she was diagnosed with estrogen dominance because:
It routes estrogen metabolites, making those metabolites safer
It optimizes liver function, which is essential during menopause
It works as an anti-inflammatory, allowing us to age well.
It works as an antioxidant, keeping our cells safer.
I have found over the last fifteen years of exclusively helping those in their "Third Act" of life that the initial plethora of symptoms associated with being paused is caused by estrogen dominance. Estrogen dominance affects both women and men.
Remember, while most clients report positive experiences with DIM, it is essential to consult a healthcare professional to tailor any supplement regimen to your needs.
There you have it, another "Third Act Hack" to look and feel great as you age.
BE COACHED FOR FREE!
If you want to learn how to optimize your hormones, weight, health, and mind, I'll teach you for FREE!
For one week, you'll learn the primary tools of The HOPE Protocol, a life optimization program.
This is what we will do:
We will put together a customized plan to optimize your hormones.
We will share the menu for "paused" women and men to lose weight.
We will teach you the tools to optimize your liver, therefore optimizing your health.
We will motivate you to be self-disciplined and teach you to eliminate bad habits.
This is how we do all this!
Accountability: you must report to us daily.
Customization: 24/7 availability to us so we can tweak the program for your life.
Knowledge: access to The HOPE Hormone Optimization Course.
Motivation: Once a week, motivating conversations with me.
THIS FREE COACHING WEEK IS AVAILABLE TO JUST TWO OF MY READERS WEEKLY!
"You'll learn everything you need to do to lose weight and feel great."
I've been retired from practice for ten years and have no employees. I want to help you because this is my God-given purpose—it better be because I have never done anything else. I want to help you optimize your hormones, weight, health, and mind. Since I am retired, I coach over the phone.
If interested, text or call me at 209-345-9799 or click one of the links below.
If you are shy or want more information before you speak to me, email me your questions.
If you don't have the time to talk to me right now, here is a link to schedule a free consultation.
THIS WEEK'S US-IE
This week was too busy to take selfies, so here is a throwback of Vicky and me hiking near our home. I plan on kinking into my nineties, so it is of the utmost importance that I follow my protocol.
“If you want to reach higher levels of health as you age, it starts today.”
And remember...
"IT'S ALL ABOUT YOUR HORMONES!"
"Because when your hormones are optimized, your weight, health, and mind will follow."
🥾 Doc
FDA Disclaimer:
The information provided in The Pause newsletter is for educational and informational purposes only. The content is not intended to diagnose, treat, cure, or prevent any disease. The statements made about hormones, weight loss, or any other health-related topics have not been evaluated by the Food and Drug Administration (FDA). Always consult with your healthcare provider before making any decisions related to your health, including starting or stopping medications, supplements, or lifestyle changes.
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